|
|
L-aspartate + L-citrulline + ATP <=> H+ + argininosuccinate + diphosphate + AMP
|
6.3.4.5
argininosuccinate synthase
|
–
|
BMK
|
|
BRENDA:
BR142;
BS408483
KEGG:
R01954
MetaCyc:
ARGSUCCINSYN-RXN
SABIO-RK:
572
|
|
|
|
H+ + L-citrulline + H2O <=> L-ornithine + CO2 + NH3
|
3.5.1.20
citrullinase
3.5.1.6
beta-ureidopropionase
|
–
–
|
B
|
|
BRENDA:
BR19238;
BS116217
KEGG:
R00665
MetaCyc:
CITRULLINASE-RXN
|
|
|
|
H2O + L-arginine <=> NH3 + L-citrulline
|
3.5.3.15
protein-arginine deiminase
3.5.3.6
arginine deiminase
|
–
–
|
BMK
|
|
BRENDA:
BR22730;
BS369889
KEGG:
R00552
MetaCyc:
ARGININE-DEIMINASE-RXN
SABIO-RK:
97
|
|
|
|
H2O + NG,NG-dimethyl-L-arginine <=> Dimethylamine + L-citrulline
|
3.5.3.18
dimethylargininase
|
–
|
|
|
BRENDA:
BR29520
KEGG:
R02513
MetaCyc:
DIMETHYLARGININASE-RXN
SABIO-RK:
2438
|
|
|
|
L-arginine + reduced_flavodoxin + O2 <=> L-citrulline + NO + flavin + H2O + H+
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
K
|
|
BRENDA:
BR40515
KEGG:
R11711
MetaCyc:
RXN-13568
|
|
|
|
L-ornithine + Carbamoyl_phosphate <=> H+ + L-citrulline + phosphate
|
2.1.3.3
ornithine carbamoyltransferase
2.1.3.6
putrescine carbamoyltransferase
3.5.3.12
agmatine deiminase
|
–
–
–
|
BMK
|
|
BRENDA:
BR43950;
BS140887
KEGG:
R01398
MetaCyc:
ORNCARBAMTRANSFER-RXN;
RXN-13482
SABIO-RK:
98
|
|
|
|
N-acetyl-L-citrulline + H2O <=> L-citrulline + acetate
|
3.5.1.16
acetylornithine deacetylase
3.5.1.B4
|
–
–
|
BMK
|
|
BRENDA:
BR48939;
BS394032
KEGG:
R09107
MetaCyc:
RXN-7933
|
|
|
|
Nomega-hydroxy-L-arginine + reduced_flavodoxin + O2 <=> L-citrulline + NO + flavin + H2O + H+
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR50159
KEGG:
R11713
MetaCyc:
RXN-13567
|
|
|
|
Nomega-hydroxy-L-arginine + NADPH + O2 <=> L-citrulline + NO + NADP+ + H2O + H+
|
1.14.13.39
nitric-oxide synthase (NADPH)
|
–
|
MK
|
|
BRENDA:
BR50160;
BS289236
KEGG:
R00111
MetaCyc:
RXN-13565
|
|
|
|
L-arginine + NADPH + H+ + O2 <=> L-citrulline + NO + NADP+ + H2O
|
1.14.13.39
nitric-oxide synthase (NADPH)
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
–
|
MK
|
|
BRENDA:
BR52111;
BS394886
KEGG:
R00557
MetaCyc:
NITRIC-OXIDE-SYNTHASE-RXN
SABIO-RK:
969
|
|
|
|
arsenate + L-citrulline <=> carbamoylarsenate + L-ornithine
|
2.1.3.3
ornithine carbamoyltransferase
|
–
|
|
|
BRENDA:
BS320103
SABIO-RK:
8025
|
|
|
|
Nomega-amino-L-arginine + H2O <=> L-citrulline + hydrazine
|
3.5.3.6
arginine deiminase
|
–
|
|
|
BRENDA:
BS382422
SABIO-RK:
7744
|
|
|
|
Ngamma-monomethyl-L-arginine + H2O <=> L-citrulline + methylamine
|
3.5.3.18
dimethylargininase
3.5.3.6
arginine deiminase
|
–
–
|
|
|
BRENDA:
BS382423
SABIO-RK:
14599;
7743
|
|
|
|
2 L-arginine + 3 NADH + 3 H+ + 4 O2 <=> 2 L-citrulline + 2 NO + 3 NAD+ + 4 H2O
|
not assigned
|
–
|
|
|
KEGG:
R10106
|
|
|
|
2 Nomega-hydroxy-L-arginine + NADH + H+ + 2 O2 <=> 2 L-citrulline + 2 NO + NAD+ + 2 H2O
|
not assigned
|
–
|
|
|
KEGG:
R10108
|
|
|
|
L-citrulline <=> L-citrulline
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-227
|
|
|
|
L-citrulline + H2O + O2 <=> N5-carbamoyl-2-oxopentanoic_acid + NH3 + H2O2
|
1.4.3.2
L-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS373561
|
|
|
|
L-citrulline + H2O + O2 <=> 2-Oxo-5-carbamidopentanoate + NH3 + H2O2
|
1.4.3.2
L-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS414757
|
|
|
|
2 L-arginine + 3 tetrahydrofolate + 4 O2 <=> 2 L-citrulline + 2 NO + 3 folate + 4 H2O
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
|
|
BRENDA:
BS438667
|
|
|
|
2 L-arginine + 3 tetrahydrobiopterin + 4 O2 <=> 2 L-citrulline + 2 NO + 3 biopterin + 4 H2O
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
|
|
BRENDA:
BS438666
|
|
|
|
2 Nomega-hydroxy-L-arginine + tetrahydrobiopterin + 2 O2 <=> 2 L-citrulline + 2 NO + biopterin + 2 H2O
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
|
|
BRENDA:
BS438668
|
|
|
|
Nomega-hydroxy-L-arginine + 2'',3''-dialdehyde-NADPH + H+ + O2 <=> 2 L-citrulline + NO + 2'',3''-dialdehyde-NADP+ + H2O
|
1.14.13.39
nitric-oxide synthase (NADPH)
|
–
|
|
|
BRENDA:
BS451278
|
|
|
|
Arginine_methyl_ester + H2O <=> L-citrulline + NH3
|
3.5.3.15
protein-arginine deiminase
|
–
|
|
|
BRENDA:
BS433865
|
|
|
|
L-citrulline + pyruvate + NADPH <=> N2-(D-1-Carboxyethyl)-L-citrulline + NADP+ + H2O
|
1.5.1.11
D-octopine dehydrogenase
|
–
|
|
|
BRENDA:
BS6367
|
|
|
|
S-methyl-L-thiocitrulline + H2O <=> methanethiol + L-citrulline
|
3.5.3.18
dimethylargininase
|
–
|
|
|
BRENDA:
BS385696
|
|
|
|
L-citrulline + H2O <=> (2S)-2-amino-5-(carboxyamino)pentanoic_acid + NH3
|
3.4.11.17
tryptophanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS382111
|
|
|
|
L-citrulline <=> D-citrulline
|
5.1.1.10
amino-acid racemase
5.1.1.9
arginine racemase
|
–
–
|
|
|
BRENDA:
BS837
|
|
|
|
ATP + H2O + L-citrulline-[L-citrulline-binding_protein][side_1] <=> ADP + phosphate + L-citrulline + [L-citrulline-binding_protein][side_1]
|
7.4.2.1
ABC-type polar-amino-acid transporter
|
–
|
|
|
BRENDA:
BS445053
|
|
|
|
ATP + H2O + L-citrulline <=> ADP + phosphate + L-citrulline
|
7.4.2.1
ABC-type polar-amino-acid transporter
|
–
|
|
|
BRENDA:
BS396502
|
|
|
|
ATP + L-citrulline + tRNACCCG <=> AMP + diphosphate + L-citryl-tRNACCCG
|
6.1.1.19
arginine---tRNA ligase
|
–
|
|
|
BRENDA:
BS428275
|
|
|
|
dATP + L-citrulline + L-aspartate <=> dAMP + diphosphate + argininosuccinate
|
6.3.4.5
argininosuccinate synthase
|
–
|
|
|
BRENDA:
BS715
|
|
|
|
phenylpyruvate + L-citrulline <=> L-phenylalanine + 2-Oxo-5-carbamidopentanoate
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
|
–
|
|
|
BRENDA:
BS356443
|
|
|
|
2 ATP + HCO3- + NH3 + L-ornithine <=> 2 ADP + 2 phosphate + H2O + L-citrulline
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
|
–
|
|
|
SABIO-RK:
9636
|
|